Population pharmacodynamics : strategies for concentration- and effect-controlled clinical trialsEBLING, W. F; LEVY, G.The Annals of pharmacotherapy. 1996, Vol 30, Num 1, pp 12-19, issn 1060-0280Article

Formulation-dependent brain and lung distribution kinetics of Propofol in RatsDUTTA, S; EBLING, W. F.Anesthesiology (Philadelphia). 1998, Vol 89, Num 3, pp 678-685, issn 0003-3022Article

Formulation-dependent pharmacokinetics and pharmacodynamics of propofol in ratsDUTTA, S; EBLING, W. F.Journal of pharmacy and pharmacology. 1998, Vol 50, Num 1, pp 37-42, issn 0022-3573Article

Parameter estimability of biphasic response modelsDUTTA, S; EBLING, W. F.Journal of pharmaceutical sciences. 1997, Vol 86, Num 1, pp 44-51, issn 0022-3549Article

Emulsion formulation reduces propofol's dose requirements and enhances safetyDUTTA, S; EBLING, W. F.Anesthesiology (Philadelphia). 1997, Vol 87, Num 6, pp 1394-1405, issn 0003-3022Article

Precursor-dependent indirect pharmacodynamic response model for tolerance and rebound phenomenaSHARMA, A; EBLING, W. F; JUSKO, W. J et al.Journal of pharmaceutical sciences. 1998, Vol 87, Num 12, pp 1577-1584, issn 0022-3549Article

Pharmacodynamic characterization of the electroencephalographic effects of thiopental in ratsEBLING, W. F; DANHOF, M; STANSKI, D. R et al.Journal of pharmacokinetics and biopharmaceutics. 1991, Vol 19, Num 2, pp 123-143, issn 0090-466X, 21 p.Article

Concentration- or effect-controlled clinical trials with sparse dataLEVY, G; EBLING, W. F; FORREST, A et al.Clinical pharmacology and therapeutics. 1994, Vol 56, Num 1, pp 1-8, issn 0009-9236Article

The determination of essential clearance, volume, and residence time parameters of recirculating metabolic systems: the reversible metabolism of methylprednisolone and methylprednisone in rabbitsEBLING, W. F; JUSKO, W. J.Journal of pharmacokinetics and biopharmaceutics. 1986, Vol 14, Num 6, pp 557-599, issn 0090-466XArticle

Propofol pharmacokinetics and pharmacodynamics assessed from a cremophor EL formulationDUTTA, S; MATSUMOTO, Y; EBLING, W. F et al.Journal of pharmaceutical sciences. 1997, Vol 86, Num 8, pp 967-969, issn 0022-3549Article

Is it possible to estimate the parameters of the sigmoid E_max model with truncated date typical of clinical studies ?SANDEEP DUTTA; MATSUMOTO, Y; EBLING, W. F et al.Journal of pharmaceutical sciences. 1996, Vol 85, Num 2, pp 232-239, issn 0022-3549Article

Feasibility of effect-controlled clinical trials of drugs with pharmacodynamic hysteresis using sparse dataEBLING, W. F; MATSUMOTO, Y; LEVY, G et al.Pharmaceutical research. 1996, Vol 13, Num 12, pp 1804-1810, issn 0724-8741Article

From piecewise to full physiologic pharmacokinetic modeling : applied to thiopental disposition in the ratEBLING, W. F; WADA, D. R; STANSKI, D. R et al.Journal of pharmacokinetics and biopharmaceutics. 1994, Vol 22, Num 4, pp 259-292, issn 0090-466XArticle

Analysis of cortisol, methylprednisolone, and methylprednisolone hemisuccinate: absence of effects of troleandomycin on ester hydrolysisEBLING, W. F; SZEFLER, S. J; JUSKO, W. J et al.Journal of chromatography. 1984, Vol 305, Num 2, pp 271-280, issn 0021-9673Article

Concentration-EEG effect relationship of propofol in ratsDUTTA, S; MATSUMOTO, Y; GOTHGEN, N. U et al.Journal of pharmaceutical sciences. 1997, Vol 86, Num 1, pp 37-43, issn 0022-3549Article

Understanding pharmacokinetics and pharmacodynamics through computer simulation. I: The comparative clinical profiles of fentanyl and alfentanilEBLING, W. F; LEE, E. N; STANSKI, D. R et al.Anesthesiology (Philadelphia). 1990, Vol 72, Num 4, pp 650-658, issn 0003-3022Article

A PC-based graphical simulator for physiological pharmacokinetic modelsWADA, D. R; STANSKI, D. R; EBLING, W. F et al.Computer methods and programs in biomedicine. 1995, Vol 46, Num 3, pp 245-255, issn 0169-2607Article

Nonlinear perpendicular least-squares regression in pharmacodynamicsKO, H. C; JUSKO, W. J; EBLING, W. F et al.Biopharmaceutics & drug disposition. 1997, Vol 18, Num 8, pp 711-716, issn 0142-2782Article

Cimetidine-methylprednisolone-theophylline metabolic interactionGREEN, A. W; EBLING, W. F; GARDNER, M. J et al.The American journal of medicine. 1984, Vol 77, Num 6, pp 1115-1118, issn 0002-9343Article

Thiopental pharmacodynamics. I: Defining the pseudo-steady state-serum concentration-EEG effect relationshipBÜHRER, M; MAITRE, P. O; HUNG, O. R et al.Anesthesiology (Philadelphia). 1992, Vol 77, Num 2, pp 226-236, issn 0003-3022Article

Disposition and exposure of the fibrinogen receptor antagonist XV459 on α_IIBβ₃ binding sites in the guinea pigBARRETT, J. S; JUN YU; PIENIASZEK, H. J et al.Biopharmaceutics & drug disposition. 1999, Vol 20, Num 6, pp 309-318, issn 0142-2782Article

Effects of thiopental on regional blood flows in the ratWADA, D. R; HARASHIMA, H; EBLING, W. F et al.Anesthesiology (Philadelphia). 1996, Vol 84, Num 3, pp 596-604, issn 0003-3022Article

6α-methylprednisolone and 6α-methylprednisone plasma protein binding in humans and rabbitsEBLING, W. F; MILSAP, R. L; SZEFLER, S. J et al.Journal of pharmaceutical sciences. 1986, Vol 75, Num 8, pp 760-763, issn 0022-3549Article

Methylprednisolone versus prednisolone pharmacokinetics in relation to dose in adultsSZEFLER, S. J; EBLING, W. F; GEORGITIS, J. W et al.European journal of clinical pharmacology. 1986, Vol 30, Num 3, pp 323-329, issn 0031-6970Article

High-performance liquid chromatographic method for determining thiopental concentrations in twelve rat tissues: application to physiologic modeling of disposition of barbiturateEBLING, W. F; MILLS-WILLIAMS, L; HARAPAT, S. R et al.Journal of chromatography. 1989, Vol 490, Num 2, pp 339-353, issn 0021-9673Article